This disease is caused by a defective protein GLUT-1 at the blood-brain barrier and brain cells level which prevents the passage of glucose, thus causing severe neurological problems in patients; in fact, normally the brain only uses glucose as an energy source. To date, a ketogenic diet is the only treatment possible; in fact, ketone bodies, unlike fat, can pass the blood-brain barrier and provide energy to the brain of affected individuals. Individuals with GLUT-1 syndrome must follow a ketogenic diet absolutely rigorously in order to lead a normal life.
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Dr. Raffaele Pilla, Pharm.D., PhD.
- External Pharmacy - Fatebenefratelli Hospital Benevento, Italy
- Operative Unit of Child and Adolescent Neuropsychiatry Faculty of Medicine and Surgery University of Salerno, Italy
- Italian Glut1 Deficit Association - www.glut1.it Scientific Committee Novate Milanese, Milan, Italy
- Morsani College of Medicine Dpt. Molecular Pharmacology and Physiology University of South Florida Tampa, Florida (U.S.A)
1. Are Le Gamberi Foods nutritional products harmful to the kidneys?
A diet made up of Le Gamberi Foods products does not cause any kidney overload as it is not a high-protein diet, simply carb-free (less 2%).
2.Is it harmful to the metabolism?
Carb-free diets tend to improve the use of fats as fuel, thereby improving the metabolism. However, we recommend you periodically reintroduce products containing carbohydrates into your diet.
3.Could ketosis induced by this diet cause problems for me?
Ketosis (a state where there is an increase in production and use of ketone bodies) is a metabolic condition that is safe where no medical conditions are present.
4.Is it true that this kind of diet raises cholesterol?
No. All the latest scientific research shows that a ketogenic diet actually helps lower triglycerides and raise the HDL fraction (that is, the protective fraction) of cholesterol.
5. What are ketone bodies?
Ketone bodies are produced by our body to ensure an absence of carbohydrates does not prevent fats from being used in our normal metabolic pathways. Fats therefore follow alternative pathways that lead to the formation of these ketone bodies which are used by our body as an energy source.